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北京兒童醫院

感染與病毒研究室
2023-01-29 09:37:50
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Jiang RM, Zheng YJ, Zhou L, Feng LZ, Ma L, Xu BP, Xu HM, Liu W, Xie ZD, Deng JK, Xiong LJ, Luo WJ, Liu ZS, Shu SN, Wang JS, Jiang Y, Shang YX, Liu M, Gao LW, Wei Z, Liu GH, Gang Liu, Xiang W, Cui YX, Lu G, Lu M, Lu XX, Jin RM, Bai Y, Ye LP, Zhao DC, Shen AD, Ma X, Lu QH, Xue FX, Shao JB, Wang TY, Zhao ZY, Li XW, Yang YH, Shen KL. Diagnosis, treatment, and prevention of monkeypox in children: an experts' consensus statement. World J Pediatr. 2022 Nov 21:1–12. doi: 10.1007/s12519-022-00624-3. Epub ahead of print. PMID: 36409451; PMCID: PMC9685019.

Yuan J, Feng Z, Wang Q, Han L, Guan S, Liu L, Ye H, Xu L, Han X. 3'UTR of SARS-CoV-2 spike gene hijack host miR-296 or miR-520h to disturb cell proliferation and cytokine signaling. Front Immunol. 2022 Sep 27;13:924667. doi: 10.3389/fimmu.2022.924667. PMID: 36238276; PMCID: PMC9552351.

Chen X, Qu X, Liu C, Zhang Y, Zhang G, Han P, Duan Y, Li Q, Wang L, Ruan W, Wang P, Wei W, Gao GF, Zhao X, Xie Z. Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18. mBio. 2022 Aug 30;13(4):e0116622. doi: 10.1128/mbio.01166-22. Epub 2022 Jul 5. PMID: 35862785; PMCID: PMC9426509.

Zhao H, Feng Q, Feng Z, Zhu Y, Ai J, Xu B, Deng L, Sun Y, Li C, Jin R, Shang Y, Chen X, Xu L, Xie Z. Clinical characteristics and molecular epidemiology of human metapneumovirus in children with acute lower respiratory tract infections in China, 2017 to 2019: A multicentre prospective observational study. Virol Sin. 2022 Dec;37(6):874-882. doi: 10.1016/j.virs.2022.08.007. Epub 2022 Aug 22. PMID: 36007839; PMCID: PMC9797368.

Liu M, Wang X, Zhang L, Feng G, Zeng Y, Wang R, Xie Z. Epidemiological characteristics and disease burden of infectious mononucleosis in hospitalized children in China: A nationwide retrospective study. Virol Sin. 2022 Oct;37(5):637-645. doi: 10.1016/j.virs.2022.07.007. Epub 2022 Jul 12. PMID: 35840103; PMCID: PMC9583177.

Feng Q, Lin S, Liu H, Yang B, Han L, Han X, Xu L, Xie Z. Meta-Analysis of Whole Blood Transcriptome Datasets Characterizes the Immune Response of Respiratory Syncytial Virus Infection in Children. Front Cell Infect Microbiol. 2022 Apr 13;12:878430. doi: 10.3389/fcimb.2022.878430. PMID: 35493728; PMCID: PMC9043598.

Zhao H, Xu W, Wang L, Zhu Y, Wang X, Liu Y, Ai J, Feng Q, Deng L, Sun Y, Li C, Jin R, Shang Y, Gao H, Qian S, Xu L, Xie Z. WU Polyomavirus Infection in Children With Acute Lower Respiratory Tract Infections in China, 2017 to 2019: Case Reports and Multicentre Epidemiological Survey. Front Cell Infect Microbiol. 2022 Mar 11;11:835946. doi: 10.3389/fcimb.2021.835946. PMID: 35360221; PMCID: PMC8963484.

Feng Z, Xu L, Xie Z. Receptors for Respiratory Syncytial Virus Infection and Host Factors Regulating the Life Cycle of Respiratory Syncytial Virus. Front Cell Infect Microbiol. 2022 Feb 25;12:858629. doi: 10.3389/fcimb.2022.858629. PMID: 35281439; PMCID: PMC8913501.

Liu J, Zhao H, Feng Z, Liu Y, Feng Q, Qian S, Xu L, Gao H, Xie Z. A severe case of human rhinovirus A45 with central nervous system involvement and viral sepsis. Virol J. 2022 Apr 22;19(1):72. doi: 10.1186/s12985-022-01799-x. PMID: 35459180; PMCID: PMC9034649.

Zhao H, Liu Y, Feng Z, Feng Q, Li K, Gao H, Qian S, Xu L, Xie Z. A fatal case of viral sepsis and encephalitis in a child caused by human adenovirus type 7 infection. Virol J. 2022 Sep 28;19(1):154. doi: 10.1186/s12985-022-01886-z. PMID: 36171632; PMCID: PMC9517974.

Zhang L, Wang R, Xie Z. The roles of DNA methylation on the promotor of the Epstein-Barr virus (EBV) gene and the genome in patients with EBV-associated diseases. Appl Microbiol Biotechnol. 2022 Jun;106(12):4413-4426. doi: 10.1007/s00253-022-12029-3. Epub 2022 Jun 28. Erratum in: Appl Microbiol Biotechnol. 2022 Nov;106(21):7373. PMID: 35763069; PMCID: PMC9259528.

Zhang L, Wang X, Liu M, Feng G, Zeng Y, Wang R, Xie Z. The epidemiology and disease burden of congenital TORCH infections among hospitalized children in China: A national cross-sectional study. PLoS Negl Trop Dis. 2022 Oct 14;16(10):e0010861. doi: 10.1371/journal.pntd.0010861. PMID: 36240247; PMCID: PMC9604879.

Wang R, Wang X, Zhang L, Feng G, Liu M, Zeng Y, Xie Z. The epidemiology and disease burden of children hospitalized for viral infections within the family Flaviviridae in China: A national cross-sectional study. PLoS Negl Trop Dis. 2022 Jul 5;16(7):e0010562. doi: 10.1371/journal.pntd.0010562. PMID: 35788743; PMCID: PMC9286261.

Zhang M, Chen X, Wang W, Li Q, Xie Z. Genetic characteristics of Coxsackievirus A6 from children with hand, foot and mouth disease in Beijing, China, 2017-2019. Infect Genet Evol. 2022 Dec;106:105378. doi: 10.1016/j.meegid.2022.105378. Epub 2022 Oct 17. PMID: 36257478.

Li Q, Wang R, Xu H, Zhang L, Fu Y, Tian J, Liu M, Feng G, Zeng Y, Chen X, Xie Z. Epidemiology and Disease Burden of Hospitalized Children With Viral Central Nervous System Infections in China, 2016 to 2020. Pediatr Neurol. 2023 Jan;138:38-44. doi: 10.1016/j.pediatrneurol.2022.09.003. Epub 2022 Oct 14. PMID: 36356470.

Wang R, Zhang M, Zhang L, Liu M, Shan C, An J, Xie Z. Japanese Encephalitis Vaccine Generates Cross-Reactive Memory T Cell Responses to Zika Virus in Humans. J Trop Med. 2022 Nov 19;2022:8379286. doi: 10.1155/2022/8379286. PMID: 36444358; PMCID: PMC9701130.

Chen X, Zhu Y, Li Q, Lu G, Li C, Jin R, Li L, Xu B, Gao L, Yin J, Xie Z. Genetic characteristics of human coronavirus HKU1 in mainland China during 2018. Arch Virol. 2022 Nov;167(11):2173-2180. doi: 10.1007/s00705-022-05541-4. Epub 2022 Jul 16. PMID: 35840864; PMCID: PMC9287133.

Zou X, Zhu Y, Li C, Duan Y, Zhang L, Guo X, Hou W, Xie Z, Lu Z. Construction of Adenoviral Vectors using DNA Assembly Technology. J Vis Exp. 2022 Jun 16;(184). doi: 10.3791/64033. PMID: 35786609.

Zhang L, Zhang M, Liu M, Ai J, Tian J, Ge H, Wang R, Xie Z. Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique. J Vis Exp. 2022 Sep 23;(187). doi: 10.3791/64671. PMID: 36149727.

Zhang L, Liu M, Zhang M, Ai J, Tian J, Wang R, Xie Z. Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis. J Vis Exp. 2022 Sep 7;(187). doi: 10.3791/64212. PMID: 36156539.

Wang R, Xie Z. Non-hepatotropic viral hepatitis and its causative pathogens: The ongoing need for monitoring in children with severe acute hepatitis of unknown etiology. Pediatr Investig. 2022 Aug 1;6(3):151-155. doi: 10.1002/ped4.12340. PMID: 36203520; PMCID: PMC9523801.

Junhong Ai (艾軍紅), Meng Zhang, Fang Jin, Zhengde Xie* (謝正德); Recombinant GII.4[P31] Was Predominant Norovirus Circulating in Beijing Area, China, 2018-2020. Virologica Sinica 2021 Apr 09.

Yali Duan, Changchong Li, Li Deng, Shuhua An, Yun Zhu, Wei Wang, Meng Zhang, Lili Xu (許黎黎), Baoping Xu, Xiangpeng Chen* (陳祥鵬), Zhengde Xie* (謝正德); Genetic Analysis of Human Adenovirus Type 7 Strains Circulating in Different Parts of China. Virologica Sinica 2021 Jun;36(3):382-392.

Yali Duan, Baoping Xu, Changchong Li, Yixiao Bao, Shuhua An, Yunlian Zhou, Aihuan Chen, Li Deng, Limin Ning, Yun Zhu (朱云), Wei Wang, Meng Zhang, Lili Xu (許黎黎), Xiangpeng Chen* (陳祥鵬), Zhengde Xie* (謝正德); Molecular Characteristics of Human Adenovirus Type 3 Circulating in Parts of China During 2014-2018. Frontiers in microbiology 2021;12:688661.

Liying Sun#, Chi Zhang#, Shuhua An#, Xiangpeng Chen (陳祥鵬), Yamei Li, Leshan Xiu, Baoping Xu, Zhengde Xie* (謝正德), Junping Peng; Comprehensive Description of Pathogens and Antibiotic Treatment Guidance in Children With Community-Acquired Pneumonia Using Combined Mass Spectrometry Methods. Frontiers in cellular and infection microbiology 2021;11:695134.

Qianyu Feng, Hongwei Zhao, Lili Xu* (許黎黎), Zhengde Xie (謝正德); N6-Methyladenosine Modification and Its Regulation of Respiratory Viruses. Frontiers in cell and developmental biology 2021;9:699997.

Xiangpeng Chen (陳祥鵬), Yun Zhu (朱云), Wei Wang, Changchong Li, Shuhua An, Gen Lu, Rong Jin, Baoping Xu, Yunlian Zhou, Aihuan Chen, Lei Li, Meng Zhang, Zhengde Xie* (謝正德); A multi-center study on Molecular Epidemiology of Human Respiratory Syncytial Virus from Children with Acute Lower Respiratory Tract Infections in the Mainland of China between 2015 and 2019. Virologica Sinica 2021 Aug 16.

Yun Zhu# (朱云), Baoping Xu#, Changchong Li#, Zhimin Chen#, Ling Cao, Zhou Fu, Yunxiao Shang, Aihuan Chen, Li Deng, Yixiao Bao, Yun Sun, Limin Ning, Shuilian Yu, Fang Gu, Chunyan Liu, Ju Yin, Adong Shen, Zhengde Xie* (謝正德), Kunling Shen*; A Multicenter Study of Viral Aetiology of Community-Acquired Pneumonia in Hospitalized Children in Chinese Mainland.Virologica Sinica 2021 Sep 15.

Huili Hu#, Huiling Deng#, Jing Bi#, Yi Xu, Shuangjie Li, Yue Xie, Xinrong Sun, Dongmeng Wang, Xufang Li, Wenxian Ouyang, Bing Hu, Yufeng Zhang, He Tang, Chunxiao Fang, Hui Zhang, Lingyun Guo, Chen Wang, Tianyi Wang, Fengxia Yang, Tao Jiang, Zhengde Xie* (謝正德), Gang Liu*; Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China: A multicenter retrospective study. Pediatr Investig 2021;5(3):188-194.

段亞麗,朱云,徐保平,李昌崇,陳愛歡,鄧力,鮑一笑,曹玲,孫云,寧麗敏,符州,劉春艷,殷菊,申昆玲,周云連,謝正德*.兒童社區獲得性肺炎中人腺病毒感染的多中心研究[J].中華兒科雜志,2019(01):27-32.

秦強,謝正德,申昆玲.美國感染病協會關于季節性流感診斷、治療、藥物預防和機構內流感暴發應對措施2018指南更新兒童相關內容解讀[J].中華實用兒科臨床雜志,2019(02):87-90.

吳喜蓉,劉鋼,錢素云,殷菊,秦強,劉軍,馮雪莉,賀建新,郭琰,謝正德,徐保平.住院兒童社區獲得性流感病毒肺炎臨床特點分析[J].中華實用兒科臨床雜志,2019(02):129-133.

艾軍紅,謝正德*.兒童呼吸道病毒感染的實驗室診斷方法及合理應用[J].中國實用兒科雜志,2019,34(02):104-108.

秦強,謝正德*.慢性活動性EBV感染的診療進展[J].傳染病信息,2019,32(02):175-180.

王巍,謝正德*.病毒感染激活和抑制炎癥小體的研究進展[J].病毒學報,2019,35(03):557-564.

劉軍,謝正德*.毛細支氣管炎的病原學及臨床流行病學特征[J].中國實用兒科雜志,2019,34(09):729-732.

張萌,段亞麗,王巍,朱云,陳祥鵬*,謝正德*.北京及其周邊地區兒童手足口病病原學監測及流行病學分析(2017-2018)[J].國際流行病學傳染病學雜志,2020(01):21-24.

王天玥,尚云曉,樊映紅,郝創利,田維敏,史瑞明,董琳,林榮軍,溫志紅,韓鋒,張曉波,朱玉林,王雪艷,張艷秋,謝正德,劉軍,劉俊峰,張赟,王秀芳,劉奉琴.霧化吸入布地奈德治療毛細支氣管炎的臨床多中心研究[J].中國實用兒科雜志,2020,35(03):213-216+221.

姜毅,陸小霞,金潤銘,鄭躍杰,徐保平,謝正德,劉智勝,林麗開,尚云曉,舒賽男,白燕,陸敏,盧根,鄧繼巋,羅萬軍,熊莉娟,劉苗,崔玉霞,葉樂平,高立偉,王永炎,王雪峰,李家福,王天有,蔣榮猛,李興旺,趙東赤,邵劍波,楊永弘,申昆玲.兒童新型冠狀病毒感染診斷、治療和預防專家共識(第二版)[J].中華實用兒科臨床雜志,2020(02):143-150.

白燕,葉樂平,秦強,高立偉,趙東赤,姜毅,鄭躍杰,徐保平,謝正德,林麗開,尚云曉,陸小霞,舒賽男,鄧繼巋,陸敏,王天有,金潤銘,楊永弘,申昆玲.嚴重急性呼吸系統綜合征冠狀病毒2感染兒童預防20[J].中華實用兒科臨床雜志,2020(02):86-91.

王巍,段亞麗,張萌,陳祥鵬,許黎黎,朱云*,謝正德*.人腺病毒7型感染激活NLRP3炎癥小體的機制研究[J].中華實驗和臨床病毒學雜志,2020(02):113-121.

趙秋虹,朱云,閆靜,關曉蕾,李秋萍,謝正德*.2011-2019年北京兒童醫院疑似麻疹病例血清IgM抗體檢測結果分析[J].中國病毒病雜志,2020,10(03):209-212.

Chen X, Xie Z. Concerning the discovery of mechanism for enterovirus B infection published in Cell. Pediatric Investigation. 2019 Sep; 3(3): 194-195.

Chen X, Zhang Y, Mao N, Zhu S, Ji T, Xu W. Intranasal immunization with coxsackievirus A16 virus-like particles confers protection against lethal infection in neonatal mice. Arch Virol. 2019;164(12):2975-2984.

Chen X, Ji T, Guo J, Wang W, Xu W, Xie Z. Molecular Epidemiology of Echovirus 18 Circulating in Mainland China from 2015 to 2016. Virol Sin. 2019;34(1):50-58.

Jianxing Yu. #, Chunyan Liu#., Yan Xiao. #, Zichun Xiang., Hongli Zhou., Lan Chen., Kunling Shen., Zhengde Xie*., Lili Ren.*, Jianwei Wang.* Respiratory Syncytial Virus Seasonality, Beijing, China, 2007-2015. Emerg Infect Dis 2019;25(6):1127-1135.

Xin Zhao. #, Guigen Zhang. #, Sheng Liu. #, Xiangpeng Chen#., Ruchao Peng., Lianpan Dai., Xiao Qu., Shihua Li., Hao Song., Zhengrong Gao., Pengfei Yuan., Zhiheng Liu., Changyao Li., Zifang Shang., Yan Li., Meifan Zhang., Jianxun Qi., Han Wang., Ning Du., Yan Wu., Yuhai Bi., Shan Gao., Yi Shi., Jinghua Yan., Yong Zhang., Zhengde Xie*., Wensheng Wei.*, George F Gao*. Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B. Cell. 2019; 177 (6) :1553-1565.

Zhang Q, Luo D, Xie Z, He H, Duan Z. The Oncogenic Role of miR-BART19-3p in Epstein-Barr Virus-Associated Diseases. Biomed Res Int. 2020;2020:5217039.

Ding, Q., Xu, L., Zhu, Y., Xu, B., Chen, X., Duan, Y., Xie, Z.*, & Shen, K.* (2020). Comparison of clinical features of acute lower respiratory tract infections in infants with RSV/HRV infection, and incidences of subsequent wheezing or asthma in childhood. BMC infectious diseases, 20(1), 387.

Gao J, Xu L, Xu B, Xie Z*, Shen K*. Human adenovirus Coinfection aggravates the severity of Mycoplasma pneumoniae pneumonia in children. BMC Infect Dis. 2020;20(1):420.

Yu, J., Qian, S., Liu, C., Xiao, Y., Xu, T., Wang, Y., Su, H., Chen, L., Yuan, B., Wang, X., Xu, B., Yang, Y., Shen, K., Xie, Z.*, Ren, L.*, & Wang, J.* (2020). Viral etiology of life-threatening pediatric pneumonia: A matched case-control study. Influenza and other respiratory viruses, 14(4), 452–459.

Shen, K., Yang, Y., Wang, T., Zhao, D., Jiang, Y., Jin, R., Zheng, Y., Xu, B., Xie, Z., Lin, L., Shang, Y., Lu, X., Shu, S., Bai, Y., Deng, J., Lu, M., Ye, L., Wang, X., Wang, Y., Gao, L., …(All authors except corresponding author contributed equally). Global Pediatric Pulmonology Alliance (2020). Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement. World journal of pediatrics : WJP, 16(3), 223–231.

Shen, K. L., Yang, Y. H., Jiang, R. M., Wang, T. Y., Zhao, D. C., Jiang, Y., Lu, X. X., Jin, R. M., Zheng, Y. J., Xu, B. P., Xie, Z. D., Liu, Z. S., Li, X. W., Lin, L. K., Shang, Y. X., Shu, S. N., Bai, Y., Lu, M., Lu, G., Deng, J. K.,…(All authors except corresponding author contributed equally). Global Pediatric Pulmonology Alliance (2020). Updated diagnosis, treatment and prevention of COVID-19 in children: experts' consensus statement (condensed version of the second edition). World journal of pediatrics: WJP, 16(3), 232–239.

Xie Z. Pay attention to SARS-CoV-2 infection in children. Pediatr Invest. 2020;4:1-4.

Han, Z. #, Rao, J. #, Xie, Z. #, Wang, C., Xu, B., Qian, S., Wang, Y., Zhu, J., Yang, B., Xu, F., Lei, X., Guo, F., Zhao, Z., Ren, L., & Wang, J. (2020). Chemokine (C-X-C motif) Ligand 4 is a Restrictor of Respiratory Syncytial Virus Infection and an Indicator of Clinical Severity. American journal of respiratory and critical care medicine, 10.1164/rccm.201908-1567OC. Advance online publication.

段亞麗, 謝正德*. 我國呼吸道感染人腺病毒的基因型流行概況. 中華實驗和臨床病毒學雜志, 2018, 32(4):430-434.

艾軍紅,謝正德*. EB病毒免疫逃避機制研究進展[J]. 中華實驗和臨床病毒學雜志, 2018, 31(1):98-102.

Lili Xu, Jun Liu, Yilin Pang, Xiaolei Guan, Suyun Qian, Zhengde Xie*, Hengmiao Gao*. Fatal encephalitis accompanied by ARDS in a child with HSV infection. Pediatr Invest. 2018, 2(3): 198-202.

Xiangpeng Chen, Jiayun Guo, Jingjie Li, Qiuping Li, Junhong Ai, Suzhen Sun*, Zhengde Xie*. Serotypes of human enteroviruses causing pediatric viral encephalitis and meningitis in Hebei province, China, from 2013 to 2015. Pediatr Invest. 2018, 2(2): 98-104. DOI: 10.1002/ped4.12037.

Xu L, Jiang X, Zhu Y, Duan Y, Huang T, Huang Z, Liu C, Xu B, Xie Z* . A Multiplex Asymmetric Reverse Transcription-PCR Assay Combined With an Electrochemical DNA Sensor for Simultaneously Detecting and Subtyping Influenza A Viruses. Front Microbiol. 2018 Jun 27;9:1405. doi: 10.3389/fmicb.2018.01405.

Zhang C, Xiu L, Xiao Y, Xie Z*, Ren L*, Peng J*. Simultaneous Detection of Key Bacterial Pathogens Related to Pneumonia and Meningitis Using Multiplex PCR Coupled With Mass Spectrometry. Front Cell Infect Microbiol. 2018,8:107. doi: 10.3389/fcimb.2018.00107. eCollection 2018.

Xu L, Gao H, Zeng J, Liu J, Lu C, Guan X, Qian S*, Xie Z*. A fatal case associated with respiratory syncytial virus infection in a young child. BMC Infect Dis. 2018, 18(1):217. doi: 10.1186/s12879-018-3123-8.

Xu C, Ai J, Zhang Q, Li T, Wu X, Xie Z*, Duan Z*. An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection. J. Vis. Exp. 2018,(133), e56515, doi:10.3791/56515 .

陳祥鵬, 郭佳運, 李靜潔, 王巍, 孫素真*, 謝正德*. 河北省兒童病毒性腦炎及腦膜炎??刹《?/span>30VP1基因特征分析. 病毒學報,2018,34(2):165-171.

Chen X, Xu B, Guo J, Li C, An S, Zhou Y, Chen A, Deng L, Fu Z, Zhu Y, Liu C, Xu L, Wang W, Shen K*, Xie Z*. Genetic variations in the fusion protein of respiratory syncytial virus isolated from children hospitalized with community-acquired pneumonia in China. Sci Rep. 2018 Mar 14;8(1):4491. doi: 10.1038/s41598-018-22826-4.

Yu J, Xie Z, Zhang T, Lu Y, Fan H, Yang D, Bénet T, Vanhems P, Shen K, Huang F, Han J, Li T, Gao Z, Ren L, Wang J. Comparison of the prevalence of respiratory viruses in patients with acute respiratory infections at different hospital settings in North China, 2012-2015. BMC Infect Dis. 2018; 18(1):72. doi: 10.1186/s12879-018-2982-3.

Ai J, Xie Z*. Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland. Front Pediatr. 2018, 6:289. doi: 10.3389/fped.2018.00289.

Yun Zhu?, Changchong Li?, Li Chen?, Baoping Xu?, Yunlian Zhou, Ling Cao, Yunxiao Shang, Zhou Fu, Aihuan Chen, Li Deng, Yixiao Bao, Yun Sun, Limin Ning, Chunyan Liu, Ju Yin, Zhengde Xie*, Kunling Shen*. A novel human coronavirus OC43 genotype detected in mainland China. Emerg Microbes Infect. 2018, 7:173. DOI 10.1038/s41426-018-0171-5.

陳麗, 朱云, 謝正德,. 社區獲得性肺炎患兒中人冠狀病毒感染的多中心研究[J]. 中國病毒病雜志, 2017, 7(3):179-184.

陳麗, 謝正德. 白細胞介素-10EB病毒相關疾病的關系研究進展[J]. 中華實用兒科臨床雜志, 2017, 32(10):791-793.

Wang J, Yu P, Xie Z, et al. A resequencing pathogen microarray method for high-throughput molecular diagnosis of multiple etiologies associated with central nervous system infection.[J]. Archives of Virology, 2017, 162(12):1-10.

Ai J, Xie Z, Gang L, et al. Etiology and prognosis of acute viral encephalitis and meningitis in Chinese children: a multicentre prospective study[J]. Bmc Infectious Diseases, 2017, 17(1):494.

Xu L, Zhu Y, Ren L, et al. Characterization of the Nasopharyngeal Viral Microbiome from Children with Community-Acquired Pneumonia but Negative for Luminex xTAG Respiratory Viral Panel Assay Detection.[J]. Journal of Medical Virology, 2017, 89(12).

Chen X, Li J, Guo J, et al. An outbreak of echovirus 18 encephalitis/meningitis in children in Hebei Province, China, 2015[J]. Emerging Microbes & Infections, 2017, 6(6):e54.

黃志卓,張樂萍, 謝正德. EB病毒感染相關疾病的基因缺陷研究進展. 中華實用兒科臨床雜志, 2016,31(22):1696-1699.

劉春艷, 謝正德. EB病毒感染相關疾病的實驗室診斷. 中華實用兒科臨床雜志, 2016,31(22):1691-1696.

艾軍紅, 謝正德, 申昆玲. EB病毒及兒童EB病毒相關疾病. 中華實用兒科臨床雜志, 2016,31(22):1683-1686.

謝正德, 申昆玲. 重視兒童EB病毒感染及其相關疾病的診治. 中華實用兒科臨床雜志, 2016,31(22):1681-1682.

Chen XP, Sun SZ, Guo JY, Li JJ, Xie ZD.Complete Genome Sequence Analysis of Echovirus 18 Associated with Aseptic Meningitis in Hebei Province, China, in 2015. Genome Announc. 2016 Oct 27;4(5). pii: e01165-16. doi: 10.1128/genomeA.01165-16.

中華醫學會兒科學分會感染學組,全國兒童EB病毒感染協作組. 《兒童非腫瘤性EBV感染相關主要疾病的診斷和治療原則建議》.中華兒科雜志,2016,54(8)563-568. (謝正德,張蕊,俞蕙執筆).

劉曉紅,謝正德. 兒童急性呼吸道多病原體混合感染的研究進展. 國際流行病學傳染病學雜志,2016,43(1)51-53.

Wang Y, Li Y, Lu R, Zhao Y, Xie Z, Shen J, Tan W. Phylogenetic evidence for intratypic recombinant events in a novel human adenovirus C that causes severe acute respiratory infection in children. Sci Rep. 2016 Mar 10;6:23014. doi: 10.1038/srep23014.

Gu H, Xie Z, Li T, Zhang S, Lai C, Zhu P, Wang K, Han L, Duan Y, Zhao Z, Yang X, Xing L, Zhang P, Wang Z, Li R, Yu JJ, Wang X, Yang P. Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus. Sci Rep. 2016 Jan 27;6:19840. doi: 10.1038/srep19840.

Wang Y, Ai J, Xie Z, Qin Q, Wu L, Liu Y, Liu C, Shen K. IL-10-592 A/C polymorphisms is associated with EBV-HLH in Chinese children.Hematology. 2016,21(2):95-98.

Gao L,  Ai J,  Xie Z,  Zhou C,  Liu C,  Zhang H,  Shen K. Dynamic expression of viral and cellular microRNAs in infectious mononucleosis caused by primary Epstein-Barr virus infection in children. Virol J. 2015 Dec 3;12(1):208. doi: 10.1186/s12985-015-0441-y.

朱云,郭佳運,謝正德,劉春艷,任麗麗,肖艷,徐保平,楊燕,錢素云,耿榮,申昆玲. 2007年至2014年北京地區兒童急性下呼吸道流感病毒感染臨床分析. 中華實用兒科臨床雜志, 2015,30(24):1883-1887.

李亞敏,周為民,趙彥杰,張晨,王延群,謝正德,譚文杰. 重癥急性呼吸道感染兒童中人腺病毒感染的型別分布及其流行病學特征. 中華預防醫學雜志, 2015,49(6): 571-573.

陳祥鵬, 張楓, 郭佳運, 朱云, 劉春艷, 謝正德. 北京地區急性呼吸道感染兒童RSV F蛋白抗原位點變異分析. 中華實驗和臨床病毒學雜志, 2015; 29(5): 409-412.

劉軍, 劉春艷, 謝正德, 任麗麗, 徐保平, 王健偉, 申昆玲. 兒童急性下呼吸道合胞病毒單一感染與混合感染臨床比較.中國實用兒科雜志, 2015; 2015,30(11):840-843.

吳凌燕,謝正德,劉亞麗, 艾軍紅,劉春艷,申昆玲. 中國北方漢族人群殺傷細胞免疫球蛋白樣受體及其配體人類白細胞抗原-Ⅰ類分子基因多態性研究.中華醫學遺傳學雜志. 2015, 32(5):651-6.

Zhou C, Xie Z, Gao L, Liu C, Ai J, Zhang L, Shen K. Profiling of EBV-Encoded microRNAs in EBV-Associated HemophagocyticLymphohistiocytosis.Tohoku J Exp Med. 2015, 237(2):117-26.

Liu C, Xiao Y, Zhang J, Ren L, Li J, Xie Z, Xu B, Yang Y, Qian S, Wang J, Shen K. Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012.BMC Infect Dis. 2015, 15(1):408.

錢藝,謝正德, 任麗麗, 劉春艷,肖艷, 徐保平 楊燕 錢素云, 耿榮,申昆玲.2007-2015年北京地區兒童急性下呼吸道感染人冠狀病毒檢測及臨床分析. 中華兒科雜志. 2015,53(9)707-711.

周晨, 謝正德,申昆玲.EBV編碼miRNA的研究進展. 中華實驗和臨床病毒學雜志. 2015,29(3):287-289.

魯偉峰,艾軍紅,劉亞麗,劉春艷,謝正德*.北京地區兒童EBV感染疾病中EBER基因變異特征分析.中華實驗和臨床病毒學雜志. 2015,29(2):124-126.

趙彥杰,陸柔劍,李亞敏,王延群,謝正德,樓永良,譚文杰. 重癥急性呼吸道感染患兒中人鼻病毒分型檢測及流行病學分析.生物技術通訊.2015,26(1):95-97.

Yamin Li,  Weimin Zhou,  Yanjie Zhao,  Yanqun Wang,  ZhengdeXie,  Yongliang Lou, Wenjie Tan*. Molecular Typing and Epidemiology Profiles of Human Adenovirus Infection among Paediatric Patients with Severe Acute Respiratory Infection in China. PLoS ONE.2015, 10(4): e0123234.doi:10.1371/journal.pone.0123234

張楓, 謝正德#. 呼吸道合胞病毒F基因及蛋白的相關研究進展. 病毒學報. 2015, 31(2): 201-206.

LiweiGao, ZhengdeXie#, Kunling Shen#. Epstein-Barr Virus Associated Infectious Diseases in Children.Am. J. Biomed. Sci. 2014,6(4), 217-228; doi: 10.5099/aj140400217

Weifeng Lu, Junhong Ai, Yali Liu, Chunyan Liu, ZhengdeXie#. Characteristics of viral IL-10 gene in Epstein–Barr virus infection in children inChina. Future Virol.2014,9(10): 891-897.

Xiang Z, Tsatsral S, Liu C, Li L, Ren L, Xiao Y, Xie Z, Zhou H, Vernet G, Nymadawa P, Shen K, Wang J. Respiratory infection with enterovirus genotype C117, China and Mongolia. Emerg Infect Dis. 2014,20(6):1075-7.

錢藝,謝正德*. 四種人新型冠狀病毒的研究進展.中華傳染病雜志, 2014,32(9):573-576.

魯偉峰, 謝正德* .Epstein-Barr 病毒EBER基因及其生物學特性研究進展. 國際流行病學傳染病學雜志, 2014, 41(1): 47-50.

劉亞麗,艾軍紅,閆靜,關曉蕾,劉春艷,謝正德*.北京地區近5年來兒童EB病毒感染疾病中BZLF1及其啟動區Zp基因特征分析[J].病毒學報,2014,30(1):9-15.

艾軍紅, 謝正德*, 劉春艷, 徐保平, 胡英惠, 申昆玲. 嬰幼兒呼吸道和胞病毒和人鼻病毒急性下呼吸道感染臨床特征及隨訪研究. 中華臨床醫師雜志, 2013,7(21):20-22.

Chen Zhang, Na Zhu, ZhengdeXie(共同第一), Roujian Lu, Bin He, Chunyan Liu, Xuejun Ma, Wenjie Tan. Viral Etiology and Clinical Profiles of Children withSevere Acute Respiratory Infections inChina.PLoS ONE, 2013, 8(8): e72606.

王亞麗,吳凌燕,秦強,謝正德,申昆玲.北京地區漢族兒童細胞因子基因多態性特征[J].中華實用兒科臨床雜志,2013,28(15):1162-1165.

劉春艷, 肖艷, 謝正德, 任麗麗, 胡英惠, 幺遠, 楊燕, 錢素云, 趙成松, 申昆玲. 20102012年門診和住院兒童急性呼吸道感染病毒病原比較分析. 中華兒科雜志, 2013, 51(4): 255-259.

Lu G, Li J, Xie Z(共同第一), Liu C, Guo L, Vernet G, Shen K, Wang J. Human metapneumovirus associated with community-acquired pneumonia in children in Beijing, China.J Med Virol. 2013, 85(1):138-43.

謝正德. 臨床醫學專業學位研究生培養中存在的問題及對策. 西北醫學教育. 2013, 21(S): 44-46.

Tang L, An J, Xie Z, Dehghan S, Seto D, Xu W, Ji Y. Genome and bioinformatic analysis of a HAdV-B14p1 virus isolated from a baby with pneumonia in Beijing, China. PLoS One. 2013;8(3):e60345.

Xiang Z, Xie Z, Wang Z, Ren L, Xiao Y, Li L, Vernet G, Paranhos-Baccalà G, Shen K, Wang J. Human enterovirus genotype C104, China [letter]. Emerg Infect Dis. 2013, 19(4): 689–691.

Naiying Mao, Yixin Ji, ZhengdeXie(共同第一), Huanhuan Wang, Huiling Wang, JunjingAn,Xinxin Zhang, Yan Zhang, Zhen Zhu, Aili Cui, Songtao Xu, Kunling Shen, ChunyanLiu,Weizhong Yang, Wenbo Xu.Human Parainfluenza Virus-Associated Respiratory Tract Infection among Children and Genetic Analysis of HPIV-3 Strains in Beijing,China. PLoS ONE. 2012, 7(8): e43893.

謝正德. EB病毒感染與兒童肝損害.臨床肝膽病雜志, 2012,28(12):893-895.

劉亞麗,閆靜,關曉蕾,艾軍紅, 謝正德.基于733例擇期手術患兒的EB病毒感染血清流行病學調查.中國循證兒科雜志.2012,7(6):450-453.

劉亞麗, 謝正德.EB病毒BZLF1基因和啟動區Zp的多態性及其相關研究進展. 國際流行病學傳染病學雜志.2012,39(3):227-230.

艾軍紅,謝正德*,劉春艷,高立偉,閆靜. 2005--2010年北京地區兒童原發性EBV感染流行株EBNAlLMPl基因特征分析.中華實驗和臨床病毒學雜志, 2012,26(5):352-355.

Qiang Q, Zhengde X, Chunyan L, Zhizhuo H, Junmei X, Junhong A, Zheng C, Henter JI, Kunling S. Killer cell immunoglobulin-like receptor gene polymorphisms predispose susceptibility to EBV associated hemophagocyticlymphohistiocytosis in Chinese children. MicrobiolImmunol. 2012, 56: 378-384.

秦強, 謝正德*, 劉春艷, 黃志卓, 王亞麗, 張寒, 趙曉曦, 申昆玲. 兒童EB病毒相關噬血細胞淋巴組織細胞增生癥NK細胞表面受體和CD107a表達.中國循證兒科雜志,2012,7(2):136-140.

王亞麗, 謝正德*, 申昆玲. 細胞因子基因多態性與EB病毒相關疾病關系的研究進展.中華臨床醫師雜志(電子版), 2012, 6(4): 133-135.

Qiang Q, Zhengde X, Shuang Y, Kunling S. Prevalence of Coinfection in Children with Epstein-Barr Virus-associated HemophagocyticLymphohistiocytosis.J PediatrHematolOncol. 2012,34(2):e45-e48.

Ai J, Xie Z*, Liu C, Huang Z, Xu J. Analysis of EBNA-1 and LMP-1 variants in diseases associated with EBV infection in Chinese children.Virol J. 2012, 11;9:13.

高立偉,謝正德*,申昆玲. 兒童EBV感染的非腫瘤性相關疾病.中國循證兒科雜志.2011,6(6):467-470.

艾軍紅, 謝正德*. EB病毒亞型/變異株及其與疾病關系的研究進展. 國際兒科學雜志,2011,38(6):568-571.

謝正德,肖艷, 劉春艷, 胡英惠, 幺遠, 楊燕, 錢素云, 耿榮,王健偉,申昆玲. 兒童急性下呼吸道感染病毒病原學2007-2010年監測.中華兒科雜志, 2011,49(10):745-749.

Guo L, Gonzalez R, Xie Z, Zhou H, Liu C, Wu C, Paranhos-Baccalà G, Vernet G, Shen K, Jin Q, Wang J. Bocavirus in children with respiratory tract infections.   Emerg Infect Dis. 2011, 17(9):1775-7.

Zhizhuo H, Junmei X, Yuelin S, Qiang Q, Chunyan L, Zhengde X*, Kunling S. Screening the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK gene mutations in Chinese children with Epstein-Barr virus-associated hemophagocyticlymphohistiocytosis.Pediatr Blood Cancer. 2012;58(3):410-4.

Lili Ren, Richard Gonzalez, ZhengdeXie(共同第一), ZhaohuiXiong, Chunyan Liu, Zichun Xiang, Yan Xiao, Yongjun Li, Hongli Zhou, Jianguo Li, Qingqing Yang, Jing Zhang, Lan Chen, Wei Wang, Guy Vernet, GláuciaParanhos-Baccalà, Kunling Shen, JianweiWang.Human parainfluenza virus type 4 infection in Chinese children with lower respiratory tract infections: A comparison study. J ClinVirol, 2011, 51(3): 209– 212.

謝正德.移植患兒的病毒感染. 實用兒科臨床雜志, 2011,26(10)725-727.

Li-Wei Gao, Zheng-De Xie, Ya-Yi Liu, Yan Wang, Kun-Ling Shen. Epidemiologic and clinical characteristics of infectious mononucleosis associated with Epstein-Barr virus infection in children in Beijing,China. World J Pediatr, 2011,7(1): 45-49.

呂典一, 秦茂權, 王燕, 高立偉, 謝正德#. 兒童造血干細胞移植患者人巨細胞病毒與皰疹病毒6型感染及相互關系. 中華實驗和臨床病毒學雜志, 2010; 24(6): 455-457.

Zichun Xiang, Richard Gonzalez, ZhengdeXie(共同第一), Yan Xiao, Jun Liu, Lan Chen, Chunyan Liu, Jing Zhang, Lili Ren, Guy Vernet, GláuciaParanhos-Baccalà, Kunling Shen,, Qi Jin, Jianwei Wang. Human rhinovirus C infections mirror those of human rhinovirus A in children with community-acquired pneumonia.JClinVirol, 2010; 49(2): 9499.

Lili Ren, Richard Gonzalez, ZhengdeXie, Yan Xiao, Yongjun Li, Chunyan Liu, Lan Chen, Qingqing Yang, Guy Vernet, GláuciaParanhos-Baccalà, Qi Jin, KunlingShen,andJianwei Wang. SaffoldCardioviruses of 3 Lineages in Children with Respiratory Tract Infections, Beijing,China. Emerg Infect Dis , 2010; 16(7): 1158-1161.

YAO Yuan (幺遠)1, DUAN Hong-mei (段紅梅)2, YAN Hui-min (閆慧敏)1, ZHEN Xiao-fang (甄小芳)1, PAN Yu-chen (潘宇琛)1, YAO Yao (姚瑤)1, CHEN Li (陳黎)1, JING Xue-fang (靖學芳)3, and CHEN Hai-lun (陳海倫)3.Clinically Controlled Study on Children's Infectious Mononucleosis Treated by Chinese Medicine.Chin J Integr Med, 2009; 15(5):347-352.

劉春艷, 肖艷, 張輝, 趙成松, 謝正德*, 申昆玲.兒童急性呼吸道感染病毒感染特點分析.中國實用兒科雜志, 2010;25(8):631-633.

謝正德.EB病毒相關噬血淋巴組織細胞增生癥.中國實用兒科雜志, 2010;25(8):580-582.

金穎康, 謝正德, 杜忠東, 楊雙, 申昆玲. 兒童Epstein-Barr病毒相關性噬血細胞性淋巴組織細胞增生癥的回顧性分析. 首都醫科大學學報,2010;31(2):192-196.

JIN Ying-kang, XIE Zheng-de, YANG Shuang, LU Gen, SHEN Kun-ling. Epstein-Barr virus-associated hemophagocyticlymphohistiocytosis: a retrospective study of 78 pediatric cases in mainland ofChina. Chin Med J. 2010;123(11) :1426-1430.

高立偉, 謝正德, 幺遠, 楊雙, 劉亞誼, 王燕, 姚瑤, 申昆玲. 兒童EB病毒感染傳染性單核細胞增多癥的臨床特征. 實用兒科臨床雜志. 2010; 25(10): 725-727.

Jin Y, Xie Z*, Lu G, Yang S, Shen K. Characterization of variants in the promoter of BZLF1 gene of EBV in nonmalignant EBV-associated diseases in Chinese children. Virol J. 2010 May 10;7:92.


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